Matol Code 22™ References WHEY PROTEIN: Enhances antibody response 1. Low, P.P.L., Rutherfurd, M.L., Cross, M.L. & Gill, H.S. Food Agric. Immunol.13, 255-264 (2001). Enhances lymphocyte activity 2. Low, P.P.L., Rutherfurd, K.J., Gill, H.S. & Cross, M.L. Int. Immunopharmacol. 3, 393-401 (2003). Stimulates Macrophages 3. Cross, M.L. & Gill, H.S. Immunol. Cell Biol. 77, 345-350 (1999). Enhances cytokine production 4. Ford, J.T., Wong, C.W. & Colditz, I.G. Immunol. Cell Biol. 79, 23-28 (2001). 5. Cross, M.L. & Gill, H.S. Immunol. Cell Biol., 77, 345-350 (1999). ARABINOGALACTAN: Stimulates pro-inflammatory cytokine production 6. Grieshop, C.M., Flickinger, E.A. & Fahey, G.C. Jr. J. Nutr., 132, 478-482 (2002). Increases T and B-Cell production 7. Nergard, C.S. et al. Carbohydr. Res. 340, 115-130 (2005). Enhances NK and macrophage activity 8. Kelly, G.S. Altern. Med. Rev. 4(2), 96-103 (1999). 9. Kim, L.S., Waters, R.F.& Burkholder, P.M. Altern. Med. Rev. 7(2), 138-149 (2002). 10. Currier, N.L., Lejtenyi, D. & Miller, S.C. Phytomedicine, 10, 145-153 (2003). ELEUTHEROCOCCUS SENTICOSUS (ROOT): Strong stimulation of phagocytosis by macrophages 11. Kimura, Y., Sumiyoshi, M. J. Ethnopharmacol. 95, 447-453 (2004). 12. Block, K.I. & Mead, M.N. Integr. Cancer Ther. 2(3), 247-267 (2003). Enhanced anti-inflammatroy cytokine activity 13. Altern. Med. Rev. 11(2), 151-155 (2006). 14. Panossian, A. et al. Phytomedicine, 9, 598-605 (2002). 15. Larsen, M.W., Moser, C., Hoiby, N., Song, Z. & Kharazmi, A. APMIS 112, 369-373 (2004). Increased T and B-Cell growth 16. Deyama, T., Nishibe, S. & Nakazawa, Y. Acta Pharmacol. Sin. 22(12), 1057-1070 (2001). 17. Kormosh, N., Laktionov, K. & Antoshechkina, M. Phytother. Res. 20, 424-425 (2006). LACTOFERRIN: Stimulates T-Cell growth and differentiation 18. Suzuki, Y.A., Lopez, V. & Lonnerdal, B. Cell Mol. Life Sci. 62, 2560-2575 (2005). 19. Artym, J., Zimecki, M., Kruzel, M.L. Immunobiology 207, 197-205 (2003). 20. Li, K.J. et al. J. Leukoc. Biol. 80, 350-358 (2006). 21. Legrand, D., Elass, E., Carpentier, M. & Mazurier, J. Cell Mol. Life Sci. 62, 2549-2559 (2005). Stimulates appropriate Th1/Th2 response depending on the disease 19. Artym, J., Zimecki, M., Kruzel, M.L. Immunobiology 207, 197-205 (2003). 21. Legrand, D., Elass, E., Carpentier, M. & Mazurier, J. Cell Mol. Life Sci. 62, 2549-2559 (2005). 22. Sfeir, R.M., Dubarry, M., Boyaka, P.N., Rautureau, M. & Tomé, D. Nutr. Immunol.,134, 403-409 (2004). 23. Curran, C.S., Demick, K.P., Mans eld, J.M. Cell. Immunol. 242(1), 23-30(2006). 24. Fischer, R., Debbabi, H., Dubarry, M., Boyaka, P. & Tomé, D. Biochem. Cell Biol. 84, 303-311 (2006). 25. Guillén, C. et al. J. Immunol. 168, 3950-3957 (2002). 26. Legrand, D., Elass, E., Carpentier, M. & Mazurier, J. Biochem. Cell Biol. 84(3), 282-290 (2006). Anti-cancer activity 24. Fischer, R., Debbabi, H., Dubarry, M., Boyaka, P. & Tomé, D. Biochem. Cell Biol. 84, 303-311 (2006). 27. Shau, H., Kim, A. & Golub, S.H. J. Leukoc. Biol. 51, 343-349 (1992). 28. Nuijens, J.H., van Berkel, P.H.C. & Schanbacher, F.L. J. Mammary Gland Biol. Neoplasia, 1(3), 285-295 (1996). MAITAKE: Promotes CTL cells that attack cancer cells 29. Mayell M. Altern. Med. Rev. 6(1), 48-60 (2001). 30. Borchers AT, Keen CL, Gershwin ME. Mushrooms, tumors, and immunity:an update. Exp. Biol. Med. (Maywood) 229, 393-406 (2004). Stimulates anti-inflammatory Th2 response 31. Kodama, N., Murata, Y. & Nanba, H. J. Med. Food 7(2), 141-145 (2004). Regulates Th1/Th2 balance 32. Inoue, A., Kodama, N., Nanba, H. Biol. Pharmacol. Bull. 25(4), 536-540 (2002). Stimulates phagocytosis and NK cytotoxicity 30. Borchers AT, Keen CL, Gershwin ME. Mushrooms, tumors, and immunity: an update. Exp. Biol. Med. (Maywood) 229, 393-406 (2004). 33. Wu, M.J. et al. J. Agric. Food Chem. 54, 2906-2914 (2006). 34. Kodama, N., Asakawa, A., Inui, A., Masuda, Y. & Nanba, H. Oncol. Rep. 13, 497-502 (2005)